Mehta, D., Vanderschuren, H.* (2021). Towards responsible communication of agricultural biotechnology research for the common good. Nature Reviews Molecular Cell Biology, https://doi.org/10.1038/s41580-021-00343-z
Zaidi, S.S.-E.-A., Mahas, A., Vanderschuren, H., Mahfouz, M.M. (2020). Engineering crops of the future: CRISPR approaches to develop climate-resilient and disease-resistant plants. Genome Biology, ,
Zorrilla-Fontanesi, Y., Pauwels, L., Panis, B., Signorelli, S., Vanderschuren, H.*, Swennen, R. (2020). Strategies to revise agrosystems and breeding to control Fusarium wilt of banana. Nature Food, 1, 599–604.
Van Der Straeten, D., Bhullar, N.K., De Steur, H., Gruissem, W., MacKenzie, D., Pfeiffer, W., Qaim, M., Slamet-Loedin, I., Strobbe, S., Tohme, Trijatmiko, K.R., Vanderschuren, H., Van Montagu, M, Zhang, C., Bouis, H. (2020). Multiplying the efficiency and impact of biofortification through metabolic engineering. Nature Communications, 11, 5203.
Soares, E., Shumbe, L., Dauchot, N., Notté, C., Prouin, C., Maudoux, O., Vanderschuren, H.* (2020) Asparagine accumulation in chicory storage roots is controlled by translocation and feedback regulation of asparagine biosynthesis in leaves. New Phytologist, 228 (3), 922-931.
Elegba, W., Gruissem, W., Vanderschuren, H.* (2020) Screening for Resistance in Farmer-Preferred Cassava Cultivars from Ghana to a Mixed Infection of CBSV and UCBSV. Plants, 9(8), 1026.
Orek, C., Gruissem, W., Ferguson, M., Vanderschuren, H.* (2020) Morpho-physiological and molecular evaluation of drought tolerance in cassava (Manihot esculenta Crantz). Field Crops Research, 255, 107861.
Zaidi, S.S.-E.-A., Vasudevan, K., Lentz, E.M., Vanderschuren, H.* (2020) Virus-induced gene silencing (vigs) in cassava using geminivirus agroclones. Methods in Molecular Biology 2172, pp. 51-64.
Mehta, D., Cornet, L., Hirsch-Hoffmann, M., Shan-e-Ali Zaidi, S., Vanderschuren, H.* (2020) Full-length sequencing of circular DNA viruses and extrachromosomal circular DNA using CIDER-Seq. Nature Protocols, 15, 1673-1689
Walsh, H.A., Vanderschuren, H., Taylor, S., Rey, M.E.C. (2019). RNA silencing of South African cassava mosaic virus in transgenic cassava expressing AC1/AC4 hp- RNA induces tolerance. Biotechnology Reports, 30;24:e00383
Kuon, J.E., Qi, W., Schläpfer, P., Hirsch-Hoffmann, M., Rogalla von Bieberstein, P., Patrignani, A., Poveda, L., Grob, S., Keller, M., Shimizu-Inatsugi, R., Grossniklaus, U., Vanderschuren, H., Gruissem, W. (2019). Haplotype-resolved genomes of geminivirus-resistant and geminivirus-susceptible African cassava cultivars. BMC Biology, 17:75.
Mangel, N., Fudge, J., Li, K-T, Wu, T-Y, Takayuki, T., Fernie, A., Szurek, B., Fitzpatrick, T.B., Gruissem, W., Vanderschuren, H.* (2019) Enhancement of vitamin B6 levels in rice expressing vitamin B6 biosynthesis de novo genes from Arabidopsis. The Plant Journal, 99, 1047-1065.
Mehta, D., Stürchler, A., Anjanappa, R.B., Shan-e-Ali Zaidi, S., Hirsch-Hoffmann, M., Gruissem, W., Vanderschuren, H.* (2019). Linking CRISPR-Cas9 interference in cassava to the evolution of editing-resistant geminiviruses. Genome Biology, 20:80.
Shan-e-Ali Zaidi, S., Vanderschuren, H.*, Qaim, M., Mahfouz, M.M., Kohli, A., Mansoor, S.,Tester, M. (2019). New plant breeding technologies for food security. Science, 363 (6434), 1390-1391.
Mehta, D., Hirsch-Hoffmann, M., Were, M., Patrignani, A., Shan-e-Ali Zaidi, S., Were, H., Gruissem, W., Vanderschuren, H.* (2019). A new full-length circular DNA sequencing method for viral-sized genomes reveals that RNAi transgenic plants provoke a shift in geminivirus populations in the field. Nucleic Acids Research, gky914.
Bull, S.E., Seung, D., Chanez, C., Mehta, D., Kuon, J.E., Truernit, E., Hochmuth, A., Zurkirchen, I., Zeeman, S.C., Gruissem, W., Vanderschuren, H.* (2018). Accelerated ex situ breeding of GBSS- and PTST1-edited cassava for modified starch. Science Advances, 4, eaat6086.
Lentz, E.M., Kuon, J.E., Alder, A., Mangel, N., Zainuddin, I.M., McCallum, E.J., Anjanappa, R.B., Gruissem, W., Vanderschuren, H.* (2018). Cassava geminivirus agroclones for Virus-Induced Gene Silencing in cassava leaves and roots. Plant Methods, 14, 73.
Anjanappa, R.B., Metha, D., Okoniewski, M., Gruissem, W., Vanderschuren, H.* (2018). Early transcriptome response to brown streak virus infection in resistant and susceptible cassava varieties. Molecular Plant Pathology, 19(2), 476–489.
Lentz, E.M., Eisner, S., McCallum, E.J., Schlegel, K., Campos, F.A.P., Gruissem, W., Vanderschuren, H.* (2018). Genetic Transformation of Recalcitrant Cassava by Embryo Selection and Increased Hormone Levels. Methods and Protocols, 1, 42.
Lecart, B., Jacquet, N., Anseeuw, L., Renier, M., Njeumen, P., Bodson, B., Vanderschuren, H., Richel, A. (2018). Nonconventional enzymatic method to determine free asparagine level in whole-grain wheat. Food Chemistry, 251, 64–68.
Rey, M.E.C., Vanderschuren, H.* (2017). Cassava mosaic and brown streak diseases: current perspectives and beyond. Annual Review of Virology, 4(1), 429–452.
Zainuddin, I.M., Fathoni, A., Sudarmonowati, E., Beeching, J.R., Gruissem, W., Vanderschuren, H.* (2017). Cassava Post-Harvest Physiological Deterioration: from Triggers to Symptoms. PostHarvest Biology and Technology, 142, 115–123.
Bull, S.E., Alder, A., Barsan, C., Kohler, M., Hennig, L., Gruissem, W., Vanderschuren, H.* (2017). FLOWERING LOCUS T triggers early and fertile flowering in glasshouse cassava (Manihot esculenta Crantz). Plants, 6(2), pii: E22.
Mangel, N., Fudge, J., Fitzpatrick, T.B., Gruissem, W., Vanderschuren, H.* (2017). Cassava vitamin B1 diversity and characterization of B1 biosynthetic genes. Journal of Experimental Botany, 68(13), 3351-3363.
Liu, S., Zainuddin, I., Vanderschuren, H., Doughty, J. Beeching, J. (2017). RNAi inhibition of feruloyl CoA 6′-hydroxylase reduces scopoletin biosynthesis and post-harvest physiological deterioration in cassava (Manihot esculenta Crantz) storage roots. Plant Molecular Biology, 94(1-2), 185-195.
Fudge, J., Mangel, N., Gruissem, W., Vanderschuren, H., Fitzpatrick, T.B. (2017). Rationalising vitamin B6 biofortification in crop plants. Current Opinion in Biotechnology, 44, 130-137.
Massart, S., Candresse, T., Gil, J., Lacomme, C., Predajna, L., Ravnikar, M., Reynard, J-S, Rumbou, A., Saldarelli, P., Škorić, D., Vainio, E.J., Valkonen, J.P.T., Vanderschuren, H., Varveri, C., Wetzel, T. (2017). A framework for the evaluation of biosecurity, commercial, regulatory and scientific impacts of plant viruses and viroids identified by NGS technologies. Frontiers in Microbiology, 8, 45.
Anjanappa, R.B., Metha, D., Maruthi, M.N., Kanju, E., Gruissem, W., Vanderschuren, H.* (2016). Characterization of brown streak virus-resistant cassava. Molecular Plant Microbe Interactions, 29 (7), 527-534.
Li, K-T, Moulin, M., Mangel, N., Albersen, M., Verhoeven-Duif, N-M, Zhang, P., Ma, Q., Fitzpatrick, T., Gruissem, W., Vanderschuren, H.* (2015). Elevated levels of bioavailable vitamin B6 in field-grown transgenic cassava. Nature Biotechnology, 33 (10), 1029-1032.
Vanderschuren, H.*, Nyaboga, E., Poon, J., Baerenfaller, K., Grossmann, J., Hirsch-Hoffmann, M., Kirchgessner, N., Nanni, P., Gruissem, W. (2014). Large-scale proteomics of cassava storage root and identification of a target gene to reduce post-harvest losses. The Plant Cell, 26(5): 1913-1924.
Nyaboga, E., Njiru, J., Nguu, E., Gruissem, W., Vanderschuren, H., Tripathi, L. (2013). Unlocking the potential of tropical root crop biotechnology in East Africa by establishing a genetic transformation platform for local farmer-preferred cassava cultivars. Frontiers in Plant Science, 4, 526.
Vanderschuren, H.*, Lentz, E., Zainuddin, I., Gruissem, W. (2013). Proteomics of model and crop plant species: Status, current limitations and strategic advances for crop improvement. Journal of Proteomics, 93: 5-19.
Vanderschuren, H.*, Boycheva, S., Li, K-T, Szydlowski, N., Gruissem, W., Fitzpatrick, T.B. (2013). Strategies for vitamin B6 biofortification of plants: a dual role as a micronutrient and a stress protectant. Frontiers in Plant Science, 4, 143, 1-7.
Vanderschuren, H.* (2012). Strengthening African R&D through effective transfer of tropical crop biotech to African Institutions. Nature Biotechnology, 30 (12), 1170-1172.
Vanderschuren, H.*, Moreno, I., Anjanappa, R.B., Zainuddin, I.M., Gruissem, W. (2012). Exploiting the combination of natural and genetically engineered resistance to cassava mosaic and cassava brown streak viruses impacting cassava production in Africa. PLoS ONE, 7 (9), e45277.
Zainuddin, I.M., Schlegel, K., Gruissem, W., Vanderschuren, H.* (2012). Robust transformation procedure for the production of transgenic farmer-preferred cassava landraces. Plant Methods, 8 (1), 24.
Bart, R., Cohn, M., Kassen, A., McCallum, E.J., Shybut, M., Petriello, A., Krasileva, K., Dahlbeck, D., Medina, C., Alicai, T., Kumar, L., Moreira, L.M., Rodrigues Neto, J., Verdier, V., Santana, M.A., Kositcharoenkul, N., Vanderschuren, H., Gruissem, W., Bernal, A., Staskawicz, B.J. (2012). High-throughput genomic sequencing of cassava bacterial blight strains identifies conserved effectors to target for durable resistance. PNAS, 109 (32), 13130.
Chetty, C.C., Rossin, C.B., Gruissem, W., Vanderschuren, H.*, Rey, M.E.C. (2013). Empowering green biotechnology in southern Africa: Establishment of a robust transformation platform for the production of transgenic industry-preferred cassava. New Biotechnology Journal, 30 (2), 136-143.
Niklaus, M., Gruissem, W., Vanderschuren, H.* (2011). Efficient transformation and regeneration of transgenic cassava using the neomycin phosphotransferase gene as aminoglycoside resistance marker gene. GM Crops, 2 (3), 193-200.
Moreno, I., Gruissem, W., Vanderschuren, H.* (2011). Reference genes for reliable potyvirus quantitation in cassava and analysis of Cassava brown streak virus load in host varieties. Journal of Virological Methods, 177(1): 49-54.
Owiti, J.A., Grossmann, J., Gehrig, P., Laloi, C., Dessimoz, C., Benn Hansen, M., Gruissem, W., Vanderschuren, H.* (2011). iTRAQ–based analysis of changes in the cassava root proteome reveals new pathways associated with post-harvest physiological deterioration. The Plant Journal, 67 (1), 145-156.
Sayre, R., Beeching, J., Cahoon, E.B., Egesi, C., Fauquet, C., Fellman, J., Fregene, M., Gruissem, W., Mallowa, S., Manary, M., Maziya-Dixon, B., Mbanaso, A., Shachtman, D., Siritunga, D., Taylor, N., Vanderschuren, H., Zhang, P. (2011). The BioCassava Plus Program: Biofortification of Cassava for Sub-Saharan Africa. Annual Review of Plant Biology, 62 (1), 251-272.
Bull, S. E., Ndunguru, J., Gruissem, W., Beeching, J. R., Vanderschuren, H.* (2011). Cassava: constraints to production and the transfer of biotechnology to African laboratories. Plant Cell Reports, 30 (5), 779-787.
Vanderschuren, H.*, Heinzmann, D., Faso, C., Stupak, M., Arga, K.Y., Laizet, Y., Leduchowska, P., Silva, N., Simkova, K. (2010). A cross-sectional study of biotechnology awareness and teaching in European high schools. New Biotechnology Journal, 31;27(6):822-8.
Bull, S. E., Owiti, J. A., Niklaus, M., Beeching, J. R., Gruissem, W., Vanderschuren, H.* (2009). Agrobacterium-mediated transformation of friable embryogenic calli and regeneration of transgenic cassava. Nature Protocols, 4 (12), 1845-1854.
Vanderschuren, H., Alder, A., Zhang, P., Gruissem, W. (2009). Dose-dependent RNAi-mediated geminivirus resistance in the tropical root crop cassava. Plant Molecular Biology, 70(3), 265-72.
Walser, M., Pellaux, R., Meyer, A., Bechtold, M., Vanderschuren, H., Reinhardt, R., Magyar, J., Panke, S., Held, M. (2009). Novel method for high throughput colony PCR screening in nanoliter-reactors. Nucleic Acids Research, 37(8):e57.
Vanderschuren, H., Akbergenov R., Pooggin M.M., Hohn T., Gruissem, W, Zhang, P. (2007). Transgenic cassava resistance to Africa cassava mosaic virus is enhanced by the virus promoter derived siRNAs. Plant Molecular Biology, 64 (5), 549-557.
Vanderschuren, H., Stupak, M., Futterer, J., Gruissem, W, Zhang, P. (2007). Engineering resistance to geminiviruses – Review and perspectives. Plant Biotechnology Journal, 5 (2), 207-220.
Stupak, M., Vanderschuren, H., Gruissem, W., Zhang, P. (2006). Biotechnological approaches to cassava protein improvement. Trends in Food Science and Technology, 17, 634-641.
Akbergenov R., Si-Ammour A., Blevins T., Amin I., Kutter C., Vanderschuren H., Zhang P., Gruissem W., Meins F.Jr, Hohn T., Pooggin M.M. (2006). Molecular characterization of geminivirus-derived small RNAs in different plant species. Nucleic Acids Research 34(2), 462-471
Zhang, P., Vanderschuren, H., Futterer, J., Gruissem, W. (2005). Resistance to cassava mosaic disease in transgenic cassava expressing antisense RNAs targeting virus replication genes. Plant Biotechnology Journal, 3 (4), 385-397.
* Corresponding author